The investment as important factor in the region's social and economic development has been considered in the article and as the part of the economic development strategy of Ukraine as a whole. Attracting investment contributes to economic and social growth of the region, introduction of new technologies, increase of production efficiency, creating quality human capital. The main types of international enterprises are a subsidiary, associate, business partner. Also the importance of local advantages of the region to increase the investment attractiveness and the main factors that determine the investment climate have been considered: the availability of resources, infrastructure, region's openness for foreign economic relations, the state of regional economic policy, size of the consumer market, crime rate, climate, level of education etc. The volume of region's foreign direct investments in recent years has been analyzed. During 2014-2015 years, a significant decrease of direct foreign investments in comparison with previous years has been found. The largest flow observed in areas such as industry and transport operations. Investment activity is concentrated around the main cities of the region. Main advantages and disadvantages of attracting foreign investments and the potential of the region have been determined. The aim of the article is analysis of investment activity in the Transcarpathian region. The following general scientific methods have been used: analysis, synthesis and comparison, statistics and calculation method. The research results are presented in charts and diagram. Further research should concern the need to improve the legislative framework for attracting and effective use of foreign investment, create specific steps to build a positive international image of the Transcarpathian region as well.